|
A caries vaccine is a vaccine to prevent and protect against tooth decay. ''Streptococcus mutans'' (''S. mutans'') has been identified as the major etiological agent of human dental caries. Several types of vaccines are being developed at research centres. Development of a vaccine for tooth decay has been under investigation for more than 30 years. In 1972, a caries vaccine was said to be in animal testing in England, and that it would have begun human testing soon. Intrinsic difficulties in developing it, coupled with lack of strong economic interests , are the reasons why no such vaccine is commercially available . ==Attempts using Antibodies== Early attempts followed a traditional approach to vaccination where normal ''S. mutans'' was introduced to promote a reaction from the immune system, stimulating antibody production. The corporation Planet Biotechnology has developed a synthetic antibody against ''S. mutans'', branded CaroRx, which it produces using transgenic tobacco plants. This product may be considered a therapeutic vaccine, applied once every several months, and is in Phase II clinical trials .〔(【引用サイトリンク】title=Planet Biotechnology Products )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Caries vaccine」の詳細全文を読む スポンサード リンク
|